Depression Essay Assignment Papers

Depression Essay Assignment Papers

Depression Essay Assignment Papers

Many people throughout the world experience some type of depression in their lives and it is one of the most common mental disorders.  The current statistic show that depression is linked to genetic, environmental, biological and is also psychological.  Depression can ben found with any age person.  A small child or an adult may have to deal with the depression that is affecting them.  Chemical imbalances in the brain is the leading cause for a person dealing with the depressive order.  The neurotransmitter is the what we call the communicator between the brain and the limbic system.  Researchers study the limbic system in the brain as this is where depression starts; especially for anxiety and stress.  The 3 major neurotransmitters; serotonin, norepinephrine, and dopamine all have direct relations with a persons’ depression and anxiety.  Depression Essay Assignment Papers

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Serotonin plays a crucial role in our brain.  It is associated with many physical actions that we may portray.  The actions associated with serotonin are mood altering, sleeping patterns, eating disorders, and aggression.  If a persons’ serotonin levels decrease, they may experience these depressive symptoms.  This can also make persons have a feeling of self-worth and suicidal feelings.

Another transmitter in the brain which is associated with the depressive disorder is dopamine.  This is the part of the brain that deals with our motivation and how we gain the feeling of self-worth and self-pleasure.  Early studies suggested that an existence of neurotransmitter norepinephrine deficiency in some certain areas of the brain resulted in depression. One main cause of depression is the reduction in the concentration of certain neurotransmitters in the brain, such as serotonin and dopamine. The decrease in the concentration of these neurotransmitters leads to disturbed neuronal signal processing which leads to alterations in the structure of the neuronal networks. These basic changes are accepted to be one of the fundamental purposes behind sorrow.The emergence of neuroimaging techniques, magnetic resonance imaging (MRI), positron emission tomography (PET) and functional fMRI, established the importance of the ‘neurocircuit of emotion’ which has been expanded to include other important brain areas and the prefrontal cortex (PFC). These brain sites and their connections, which have been widely studied, are responsible for maintaining emotional stability and their malfunction is considered central to the pathophysiology of depression (Palazidou, E., 2012).  Depression Essay Assignment Papers

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Recent follow up studies also shows that there is a group of individuals with a depression disorder who exhibit low levels of the chemical norepinephrine. In autopsy studies, it has been shown that in comparison, people who lives have been marred with a recurrence of depressive episodes possess lesser norepinephrinergic neurons unlike those who have not had depressive history. Norepinephrine assist our bodies detect and respond to stressful instances.  Autopsy studies also shows the cingulate cortex has been observed to be less active in people who are depressed and hyperactive in people who are manic.  The anterior portion of the cingulate cortex, unlike the rest of this structure, becomes more active during depression. Though the functions of the anterior cingulate cortexare highly complex, it seems to act somewhat like an interface between the lower, more instinctive parts of the brain and the more rational circuits of the neocortex. In healthy people, the activation of this structure would thus help to focus attention on certain phenomena, often arising from our own bodies, such as pain, or the negative feelings associated with depression (Dubuc, B., 2002).People who are susceptible to depression have a norepinephrinergic system which does not take care of the effects of stress very well. Depression Essay Assignment Papers

There has been many studies and compiled evidence that persons with stress and depression could involve different structural variations in the brain.These variations are referred to as remodeling. An occurrence of remodeling due to stress can be prevented or even potentially turned back with the correct treatment involving use of antidepressant as well as mood-stabilizing medication (Regaine, J.  2015).Additionally, there have been studies of the brain with imaging.  The studies informed us that there are parts of the brain that co-inside with the persons mood, how they make decisions, and memory may have size and functional changes,about, how a person reacts with depression.“Depression is more than a “chemical imbalance,” it’s actually a complicated physiological illness that involves both brain structure and biological processes” (Rajkowska, G. 1999).

The three structures of the brain as stated earlier, helps the brain decide what is stressful and/or depressive and how to respond.  It has been stated that a person with a depressive disorder may have a weakening of this part of the brain. Depression Essay Assignment Papers

References

Advokat, C. D., Comaty, J. E., & Julien, R. M. (2014). Julien’s primer of drug action: A comprehensive guide to the actions, uses, and side effects of psychoactive drugs (13th ed.). New York, NY: Worth Publishers.

Anacker, C. S.-G. (2016). Neuroanatomic differences associated with stress susceptibility and resilience. Biological psychiatry, 79(10), 840-849.

Palazidou, E. (2012). The neurobiology of depression. British Medical Bulletin, 101(1). 127–145. Retrieved from 

 

Depression Essay Assignment Papers

Rajkowska, G. (1999). Brain Changes Seen in People with Depression. University of Mississippi Medical Center. Retrieved from https://www.sciencedaily.com/releases/1999/05/990505071039.htm

Regiane Joca, S. A. (2015). Atypical Neurotransmitters and the Neurobiology of Depression. CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS & Neurological Disorders), 14(8), 1001-1011.

Singhal, G. J. (2015). Inflammasomes in neuroinflammation and changes in brain function: a focused review. Neuroinflammation and Behaviour, 51. Depression Essay Assignment Papers

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